If the first single, "Fresh Blood," didn't make it clear, this trailer for the making-of documentary suggests that Eels' Hombre Lobo is going to be a rock album, possibly in the vein of Souljacker. I'm positively loving "Fresh Blood," and I hope there's more like it on the album.
Update, 5/6/2009: According to the Eels camp, Hombre Lobo is indeed going to be somewhat Souljacker-ish.